The algorithm of single-channel adaptive notch filter in the active vehicle interior noise control system was deduced and corresponding evaluating indicator was established. By means ofmodelling the path of secondary acoustic signal according to a prototype car, the influence of secondary paths modelling mismatch was investigated. It was found that the system is not robust to the variation of windows open and close states. Hence, a method of robust design was put forwarded to optimize the model of secondary path and the convergence coefficient in the adaptive algorithm. The active interior noise control experiment based on rapid control prototype(RCP)in- dicated that the system after robust design was able to converge quickly and control target noise under different windows open and close states, which verify the effectiveness of robust design introduced in this paper.