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目的:针对宁波镇海工业区居民气道反应性及脉冲振荡法(IOS)测气道阻力指标情况进行调研。方法:以随访形式对镇海工业区(215例)和城区(203例)两地人群气道反应性和呼吸功能进行调研,比较分析不同区域人群的差异程度。结果:工业区215例研究对象中气道高反应性疑似者达95例,而城区203例中仅43例疑似者。工业区组95例中有47例(49.5%)为激发阳性者,而城区组43例中仅有14例(32.6%)。两区域人群在不同气道高反应性类型中的比例均差异有统计学意义(P<0.01)。城区人群在气道阻力各指标上亦均小于工业区,且均差异有统计学意义(P<0.05)。结论:工业区居民在气道高反应性患病率及IOS气道阻力方面均高于城区居民,监测和评价该地区居民上气道疾病,炎症病变程度和呼吸功能对于了解局部中重度污染区域均有一定意义。
OBJECTIVE: To investigate the airway reactivity and pulse pressure (IOS) resistance index of residents in Zhenhai Industrial Park, Ningbo. Methods: The airway responsiveness and respiratory function were investigated in the following two groups: 215 in Zhenhai Industrial Park and 203 in urban areas. The differences among different groups were compared. Results: Of the 215 study subjects in the industrial zone, 95 cases were suspected of airway hyperresponsiveness, compared with 43 cases of suspected 203 cases in the urban area. Forty-seven (49.5%) of the 95 industrialized patients in the industrial zone group were positive for the challenge, compared with 14 (32.6%) in the urban district group. There was significant difference in the proportions of different airway hyperresponsiveness between the two regions (P <0.01). The urban population in the airway resistance index are also smaller than the industrial area, and the differences were statistically significant (P <0.05). Conclusion: Residents in industrial area are higher than urban residents in the prevalence of airway hyperresponsiveness and airway resistance in IOS, and monitoring and evaluating the upper airway disease, degree of inflammation and respiratory function in residents of this area. All have some meaning.