CHARACTERIZATION OF THE CHLOROTHRICIN BIOSYNTHETIC GENE CLUSTER FROM STREPTOMYCES ANTIBIOTICUS DSM 4

来源 :15th International Symposiium on the Biology of Actinomycete | 被引量 : 0次 | 上传用户：sjtygk

【摘要】

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【作者】

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Xin-Ying Jia Qinli-he Zhen-Hua Tian Lei Shao Xu-Dong Qu Oun-Fei Zhao Jian Tang Gong-Li Tang Wen Liu

【机构】

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Shanghai Institute of Organic Chemistry Chinese Academy of Sciences,Shanghai,China

【出处】

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15th International Symposiium on the Biology of Actinomycete

【发表日期】

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2009年12期

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　　The biosynthetic gene cluster for chlorothricin (CHL) was localized to a 122 kb contiguous DNA from Streptomyces antibioticus DSM40725,and its involvement in CHL biosynthesis was confirmed by gene inactivation and complementation.Bioinformatic analysis of the sequenced 111.989 kb DNA region revealed 42 open reading frames,35 of which were defined to constitute the CHL gene cluster.

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