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There are accumulating data indicating the non-gonadal functions of DMRT / Dmrt transcription factors.For examples, Dmrt2 is related to somitogenesis and left-right asymmetry development.Dmrt4 is probably related to folliculogenesis in mouse,while Dmrt4 plays a key role in olfactory neurogenesis in X.laevis.Here, we cloned Dmrt5 from X.tropicalis and investigated its expression pattern.Our data shows that Dmrt5 have overlapping expression regions with Dmrt4 on olfactory placode and dorsal telencephalon.We therefore wonder whether there is redudency between Dmrt4 and Dmrt5 during olfactory neurogenesis.Genome wide analysis were performed on Dmrt5 overexpressed animal caps by Affymetrix chips.