It is highly desirable in analytes detection,medical diagnostics and stimulant control to develop ideal molecular sensors that should not only exhibit high specificity,sensitivity and quick response,but also be easily regenerable and simply operational for assays.Although some progress has been made to improve the performances of sensors by utilizing mimic antibodies,label-free affinity assays and immunoassays,it is still a challenge to find an efficient and general way to construct an extensively practicable sensor that simultaneously possesses above mentioned desirable features,rather than improve one feature but lose another.