【摘 要】
：
Biologically active molecules play essentials role in cellular processes.However,due to their extremely low concentration and very short life,it is difficul
【机 构】
：
CollegeofChemistry,ChemicalEngineeringandMaterialsScience,ShandongNormalUniversity,KeyLaboratoryofMo
【出 处】
：
2016年分析化学前沿国际研讨会及中美分析化学研讨会
论文部分内容阅读
Biologically active molecules play essentials role in cellular processes.However,due to their extremely low concentration and very short life,it is difficult to accurately monitor these active molecules in live cells and in vivo.Therefore,based on specific recognition reactions,we have constructed a series of new fluorescent probes that have characteristics of high ultra-high sensitivity and reversibility,and developed new principles and methods for real-time and in situ fluorescence imaging of intracellular reactive molecules,such as superoxide anion,and glycoproteins,and give new insight into the regulation of their cell functions.
其他文献
Cisplatin has long been recognized for its antitumor activity,but produces severe cytotoxicity.DNA is widely accepted as cisplatins primary target.Cisplatin
Subcellular targeting strategy has redefined the frontier of life processes as well as drug design [1].Labeling the organelles or biomacromolecules with flu
In this Presentation,the challenges and resolutions for studying molecular interaction by NMR spectroscopy in biological system,such as blood plasma and liv
Surface-enhanced Raman scattering(SERS)has become one of the most valuable tools in chemistry,biology and materials science.1 In particular,by integrating t
We have been developing direct sampling analysis method and miniature mass spectrometry(MS)systems for point-of-care analysis of biological samples.Lipids a
We make use of the distance dependence of the electrospray process to realize a new form of scanning probe microscopy,which we describe here as scanning ele
We live in an incredible age of microscopy,where a wide range of techniques are available to visualize the structure and properties of surfaces and interfac
Achieving high-resolution imaging of bone-cracks and even monitoring them in live organisms are of great significance for understanding their extreme biolog
In-depth understanding of the mechanism of virus infection is the basis for prevention and treatment of viral diseases.Labeling techniques with organic fluo