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As obligate intracellular parasites, viruses need to hijack and divert a set of cellular functions to multiply in the host.In many times, this involves protein-protein interactions (PPIs).Identification and characterization of these PPIs are crucial to dissect the molecular processes underlying viral infection and may provide new targets for virus control.Tomato yellow leaf cud Guangdong virus (TYLCGuV) is a prevalent virus causing tomato yellow leaf cud disease (TYLCD) in Guangdong province,China.