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5. A regulatory circuit of miR-143 and DNMT3a mediated vascular smooth muscle cells proliferation induc

A regulatory circuit of miR-143 and DNMT3a mediated vascular smooth muscle cells proliferation induc

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：scetc203

【摘 要】

：

Accumulating evidence has strongly suggested that homocysteine (Hcy) is an independent risk factor of atherosclerosis (AS).Hcy can promote vascular smooth muscle cells (VSMCs) proliferation,which play

【作 者】

：

Yanhua Wang Huiping Zhang Chengjian Cao Shengchao Ma Xiaoming Yang Xiaoling Yang Anning Yang Jue Tian Hua Xu Yideng Jiang 

【机 构】

：

Department of Laboratory Medical,Ningxia Medical University,Yinchuan,750004

【出 处】

：

中国生理学会第24届全国会员代表大会暨生理学学术大会

【发表日期】

：

2014年7期

【关键词】

：

miR-143 DNA-methyltransferase 3a (DNMT3a) DNA methylation VSMCs proliferation Ho 

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　　Accumulating evidence has strongly suggested that homocysteine (Hcy) is an independent risk factor of atherosclerosis (AS).Hcy can promote vascular smooth muscle cells (VSMCs) proliferation,which play a pivotal role in the pathogenesis and progression of AS.Dysregulation of microRNAs is a common feature in AS.

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