Objectives: This study was to analyzed the demographic,epidemiological,clinical and laboratory characteristics,treatment options,and outcome in patients with spine involvement in brucellosis.Methods: The data of 67 patients with spinal brucellosis out of 842 treated in the Department of Brucellosis,HulunBuir Peoples Hospital from January 2011 to December 2016 were analyzed in this study.Results: The mean age of patients was 50.5±10.2 years(43 males and 24 females; age range 29–70).The risk factors for transmission are direct contact with animals,such as working in the farm,and consumption of unpasteurized milk or daily products.Back pain(92.5%),fever(85.1%),sweating(62.7%),and fatigue(52.8%)were the most common symptoms.Magnetic resonance imaging(MRI)was performed in all the patients with spondylodiscitis.The sites of involvement were lumbar(81.2%),thoracic(8.7%),cervical(4.3%),thoracolumbar(2.9%)and lumbosacral(2.9%).The antimicrobial therapy for spinal brucellosis lasted for at least 3 months.In the presence of paravertebral or epidural abscess,longer treatment was conducted to avoid possible sequelae.Conclusions: In endemic areas such as HulunBuir,brucellar spondylitis should be considered in patients with back pain and fever.MRI is a highly sensitive imaging modality that can be used to differentiate brucellar spondylitis from other spinal infections.