@@ Ciguatera fish poisoning (CFP) or ciguatera is the most frequently reported seafood-toxin illness in the world, caused by the consumption of coral reef fishes contaminated with a group of natural marine toxins produced by marine dinoflagellates. Manifestations of CFP in humans usually involve a combination of gastrointestinal, neurological, and cardiovascular disorders. Possible symptoms include nausea, vomiting, watery diarrhea, numbness and tingling around the lips, tongue and mouth. In extreme cases, paralysis and death can occur. The occurrence of CFP in Hong Kong has increased in recent years with increasing international trade in seafood. The major risk from CFP at present is due to the importation of live reef fish caught from regions of high ciguatera risk, e.g. Republic of Kiribati, a global hotspot of CFP occurrence. Past records show that the incidence of CFP is unpredictable but is increasing, with most cases associated with fish imported from Indonesia and the islands of the South Pacific Oceans.