Synergistic antitumor activity of regorafenib and lapatinib in preclinical models of human colorecta

来源 :2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 | 被引量 : 0次 | 上传用户：caiyoutian

【摘要】

：

Regorafenib significantly prolongs overall survival in patients with metastatic colorectal cancer(mCRC),but the overall clinical efficacy of regorafenib remains quite limited.Combination chemotherapy

【作者】

：

Wen-Ji Zhang Meng-Ning Wei Yao Chen Dong-Hua Yang Zhe-Sheng Chen Zhi Shi

【机构】

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Department of Cell Biology & Institute of Biomedicine,National Engineering Research Center of Geneti

【出处】

：

2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会

【发表日期】

：

2016年10期

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　　Regorafenib significantly prolongs overall survival in patients with metastatic colorectal cancer(mCRC),but the overall clinical efficacy of regorafenib remains quite limited.Combination chemotherapy is a potentially promising approach to enhance anticancer activity,overcome drug resistance,and improve disease-free and overall survival.

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