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大脑发育是一个复杂的相互作用的过程,其早期分裂能对后来的功能性改变产生长期影响。此过程是通过复杂的细胞内和细胞间信号通道将信号即时传入和传出而实现的。长链多不饱和脂肪酸(LC-PUFA),特别是花生四烯酸和二十二碳六烯酸(DHA)在大脑发育过程中迅速聚集于大脑灰质,脑脂肪酸组成成分反映了膳食的状况。膜脂成分能以不同方式影响信号传导的级联效应.就 LC-PUFA 来讲,其作用方式是通过二十碳(烷)类介导各种重要调节功能,并可通过影响基因转录实现长期调控。我们的研究工作证明与特定脂肪酸缺乏相同,脂肪酸不平衡也会对包括对
Brain development is a complex process of interaction whose early division can have long-term effects on later functional changes. This process is achieved through the complex intracellular and intercellular signal channels that transmit and receive signals in real time. Long-chain polyunsaturated fatty acids (LC-PUFA), particularly arachidonic acid and docosahexaenoic acid (DHA), rapidly accumulate in the gray matter of the brain during brain development. The brain fatty acid composition reflects dietary conditions. Membrane lipid components can affect signaling cascades in different ways. In the case of LC-PUFA, the mode of action is through the icosa (alkanes) classes that mediate various important regulatory functions and can effect long-term Regulation. Our research shows that the same lack of specific fatty acids, fatty acid imbalance will also include the right