论文部分内容阅读
Objective To investigate the correlation between enhancement patterns of intrahepatic cholangiocarcinoma (ICC) on contrast-enhanced ultrasound (CEUS) and pathological findings.Methods The CEUS enhancement patterns of 40 pathologically proven ICC lesions were retrospectively analysed.Pathologically, the degree of tumour cell and fibrosis distribution in the lesion was semi-quantitatively evaluated.Results 4 enhancement patterns were observed in the arterial phase for 32 mass-forming ICCs: peripheral rim-like hyper-enhancement (n =19);heterogeneous hyper-enhancement (n =6);homogeneous hyper-enhancement (n =3);and heterogeneous hypo-enhancement (n=4).Among the four enhancement patterns, the differences in tumour cell distribution were statistically significant (P<0.05).The hyper-enhancing area on CEUS corresponded to more tumour cells for mass-forming ICCs.Heterogeneous hyper-enhancement (n=2) and heterogeneous hypo-enhancement (n=2) were observed in the arterial phase for four periductal-infiltrating ICCs.In this subtype, fibrosis was more commonly found in the lesions.Heterogeneous hyper-enhancement (n=l) and homogeneous hyper-enhancement (n=3) were observed in the arterial phase for four intraductal-growing ICCs.This subtype tended to have abundant tumour cells.Conclusion The CEUS findings of ICC relates to the degree of carcinoma cell proliferation at pathological examination.Hyper-enhancing areas in the tumour always indicated increased density of cancer cells.