• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. 乙肝病毒包膜蛋白主要亲水区N糖基化变异与乙肝病毒免疫逃避

乙肝病毒包膜蛋白主要亲水区N糖基化变异与乙肝病毒免疫逃避

来源 :第二届全国病毒性肝炎慢性化重症化基础与临床研究进展学术会议 | 被引量 : 0次 | 上传用户：xxlxxl123
【摘 要】
：
Background and Aims:Hepatitis B virus immune escape gives a challenge to prevention,diagnoses and treatment to hepalitis B.The aim of this study was to explore characteristics and its molecular mechan
【作 者】
：
于德敏 李新华 廖祥伟 韩悦 龚启明 张东华 张欣欣 
【出 处】
：
第二届全国病毒性肝炎慢性化重症化基础与临床研究进展学术会议
【发表日期】
：
2012年11期
【关键词】
：
HBsAg Major hydrophilicregion N-glycosylation immune escape mutation 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Background and Aims:Hepatitis B virus immune escape gives a challenge to prevention,diagnoses and treatment to hepalitis B.The aim of this study was to explore characteristics and its molecular mechanism of HBV immune escape in HBVendemic area.Methods:HBV isolates from 210 patients with coexistence of HBsAg/HBsAb were sequenced for HBsAg major hydrophilic region (MHR) analysis.
其他文献
免疫抑制剂治疗延长HBV在高压水小鼠模型中的复制及其分子机制的研
目的：利用尾静脉高压水注射技术，将pAAV/HBV1.2注射到BALB/c小鼠中产生短暂的HBV复制，探讨HBV清除或持续复制的免疫学机制。方法：分别用重组乙肝疫苗皮下注射、HBcAg特异性的脾细胞过继免疫、初始小鼠脾细胞过继免疫治疗HBV复制小鼠。结果：用乙肝疫苗或特异性T细胞过继免疫能有效清除或控制HBV的复制。结论：免疫抑制剂治疗能有效延长HBV在高压水注射模型中的复制。免疫调节治疗如乙肝疫
会议
乙型肝炎免疫抑制剂分子机制
慢性丙肝干扰素抗病毒治疗中CD4+/CD8+T淋巴细胞水平变化的临床观察及探讨
目的：探讨丙肝抗病毒治疗前后与CD4+/CD8+T淋巴细胞之间的关系。方法：对22例患者治疗3月时的CD4+/CD8+T淋巴细胞计数的X±S，并对其进行统计学分析。结果：治疗3月时的CD8+T淋巴细胞计数的原始数据进行进行两两的配对t检验，结果显示无统计学意义。结论：对于22例患者，治疗开始时，治疗1月，及治疗3月时随访的CD4及CD8分别行两两比较无统计学意义。聚乙二醇干扰素a-2a联合利巴韦林
会议
慢性丙肝病毒干扰素T淋巴细胞临床观察
Entecavir Treatment Prevents Disease Progression in HBV Related Acute-on-Chronic Liver Failure:Estab
Background/Aims:Hepatitis B related acute-on-chronic liver failure has a poor prognosis with very high mortality.Unfortunately,most prognostic predictive models of liver failure are complicated and of
会议
BLiver histology and related factors analysis in patients with chronic hepatitis B virus infection w
会议
Long-term clinical outcome of patients with chronic hepatitis B after withdrawal of antiviral therap
会议
Pathogenesis of Fibrosing Cholestatic Hepatitis BPost-Liver Transplantation
Aim:Fibrosing cholestatic hepatitis (FCH) is a particular type of liver failure that was first reported in patients with recurrent HBV after liver transplantation (LT) and termed in the Journal of Hep
会议
cholestaticliver transplantationrecurrent hepatitis Bhepatocellular cytopathi
The Characterization of serum HBV full-length genome in chronic severe hepatitis B patients and its
Objective To characterize serum Hepatitis B Virus (HBV) full-length genome in chronic severe hepatitis B (CSHB) patients and its related significance to the clinical manifestation and outcomes.Methods
会议
Hepatitis B virusHepatitis BChronicMutationGenetic HeterogeneitySevere Hepa
Enhancing anti-hepatitis B virus mediated immune response by nucleos(t)ide analogs and Thymosin-alph
会议
Enhanced expression of potassium ion channel gene KCNJ15 is associated with Acute-on-chronic Hepatit
Background & Aims Increased KCNJ 15 expression has been found in patients with hepatitis B virus (HBV)-induced Acute-on-chronic liver failure (HBV-ACLF) in previous gene microarray study.However,the m
会议
KCNJ15CD4 T cellvirus induced liver injuryacute on chronic liver failurehepa
Core-APOBEC3C chimerical protein inhibits hepatitis B virus replication
会议