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目的分析细辛脑注射液和多索茶碱联合治疗儿童支气管哮喘急性发作的临床效果。方法随机选取2011年1月1日-2015年1月1日期间的60例儿童支气管哮喘急性发作患儿,将接受基础综合治疗的患儿设为对照组(30例),接受细辛脑注射液和多索茶碱联合治疗的患儿设为试验组(30例)。观察并比较两组临床治疗结果。结果对照组患儿的呼吸困难消失时间、咳嗽消失时间、哮鸣音消失时间和住院时间分别为(4.98±1.32)d、(5.71±1.43)d、(6.44±1.30)d和(7.57±1.21)d,均长于试验组患儿[(2.11±0.91)d、(3.01±0.45)d、(4.21±0.54)d、(5.77±0.64)d],差异均有统计学意义(t=5.45,P<0.05;t=6.37,P<0.05;t=7.52,P<0.05;t=6.43,P<0.05)。试验组的治疗有效率(96.67%)优于对照组(73.33%),差异有统计学意义(χ2=5.81,P<0.05)。结论细辛脑注射液和多索茶碱联合治疗儿童支气管哮喘急性发作的效果理想,临床症状明显缓解,不良反应少,可考虑于合理范围内加大推广与应用。
Objective To analyze the clinical efficacy of Asarone Injection and doxofylline in the treatment of children with acute attack of bronchial asthma. Methods Sixty children with acute bronchial asthma were randomly selected from January 1, 2011 to January 1, 2015. The children receiving basic comprehensive treatment were selected as the control group (n = 30) and received asarone injection The combination of liquid and doxofylline in children as the experimental group (30 cases). Observe and compare two groups of clinical treatment results. Results The disappearance of dyspnea, disappearance of cough, disappearance of wheeze and hospital stay in the control group were (4.98 ± 1.32) d, (5.71 ± 1.43) d, (6.44 ± 1.30) d and (7.57 ± 1.21 ) d were longer than those in the experimental group [(2.11 ± 0.91) d, (3.01 ± 0.45) d, (4.21 ± 0.54) d, (5.77 ± 0.64) d] respectively, with statistical significance (t = 5.45, P <0.05; t = 6.37, P <0.05; t = 7.52, P <0.05; t = 6.43, P <0.05). The treatment group (96.67%) was better than the control group (73.33%), the difference was statistically significant (χ2 = 5.81, P <0.05). Conclusions Asarone injection and doxofylline are effective in treating acute exacerbation of bronchial asthma in children. The clinical symptoms are obviously relieved and the adverse reactions are few. It can be considered to promote and apply within a reasonable scope.