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目的探究射频热疗在恶性腹水的综合治疗中的临床疗效,为恶性腹水的治疗提供参考经验。方法选取2009年10月—2011年5月恶性腹水患者85例,包括卵巢癌32例,胃癌16例,肝癌11例,胰腺癌5例,结肠直肠癌15例,乳腺癌6例,随机分为治疗组和对照组。治疗组给予局部射频热疗联合腹腔灌注化疗药物,对照组只给予腹腔灌注化疗药物。观察两组的腹水消退情况、卡氏评分变化及治疗中出现的不良反应。结果治疗组有效率(CR+PR)75.6%,卡氏评分升高率76.2%,与对照组有明显差异(P<0.05),而且不良反应两组间无明显差异(P>0.05)。结论局部射频热疗联合腹腔灌注化疗药物治疗恶性腹水效果更好,且不增加不良反应,值得推广。
Objective To explore the clinical effect of radiofrequency thermotherapy in the comprehensive treatment of malignant ascites and provide reference experience for the treatment of malignant ascites. Methods Eighty-five patients with malignant ascites from October 2009 to May 2011 were selected, including 32 cases of ovarian cancer, 16 cases of gastric cancer, 11 cases of hepatocellular carcinoma, 5 cases of pancreatic cancer, 15 cases of colorectal cancer and 6 cases of breast cancer. Treatment group and control group. The patients in the treatment group received local radiofrequency thermotherapy combined with intraperitoneal chemotherapy and the control group received intraperitoneal chemotherapy. Observation of two groups of ascites regression, changes in the card’s score and treatment of adverse reactions. Results The effective rate of CR + PR was 75.6% in treatment group and 76.2% in Karnofsky ’s score group, which was significantly different from that in control group (P <0.05). There was no significant difference between the two groups (P> 0.05). Conclusion Local radiofrequency thermotherapy combined with intraperitoneal chemotherapy of malignant ascites is better, and does not increase adverse reactions, it is worth promoting.