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目的血清心肌肌钙蛋白I(cTnI)、肌红蛋白(Mb)和肌酸激酶(CK)在诊断急性心肌梗死(AMI)中的临床意义。方法对急性AMI患者在不同时间抽血检测cTnI、Mb、CK,计算其阳性率。结果 AMI患者在6h检测时的阳性率最高为Mb(94.0%),骨骼肌损伤时Mb和CK的阳性率也较高;cTnI的特异性最高,Mb和CK的特异性较差,因此3个项目联合检测时确诊率才是最高。结论因cTnI、Mb、CK均受多因素影响,各自用来检测心肌梗死具有一定局限性,联合检测才能提高急性AMI确诊的速度和确诊率。
Objective To investigate the clinical significance of serum cardiac troponin I, Mb and creatine kinase (CK) in the diagnosis of acute myocardial infarction (AMI). Methods Acute AMI patients at different times of blood cTnI, Mb, CK, calculate the positive rate. Results The highest positive rate of AMI was Mb (94.0%) at 6h, the positive rate of Mb and CK was higher at skeletal muscle injury. The specificity of cTnI was the highest, and the specificity of Mb and CK was poor. Therefore, 3 The joint diagnosis of the project is the highest rate of diagnosis. Conclusions Because cTnI, Mb and CK are all influenced by many factors, each of them has some limitations to detect myocardial infarction. Combined detection can improve the speed and the diagnosis rate of acute AMI.