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[目的]观察瓜蒌薤白半夏汤联合西药治疗痰浊闭阻型冠心病心绞痛疗效。[方法]使用随机平行对照方法,将80例门诊及住院患者按抛硬币法简单随机分为两组。控制糖尿病、高血压及高血脂等,健康教育,避免心绞痛诱发因素,抗凝、抗血小板聚集等治疗。对照组40例硝酸异山梨酯,10mg/次,2~3次/d。治疗组40例瓜蒌薤白半夏汤(瓜蒌、葛根各25g,白芍20g,丹参、薤白各15g,半夏、桂枝、人参、郁金、延胡索、柴胡各10g),1剂/d,水煎150mL,早晚口服,75mL/次;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、心绞痛发作次数、不良反应。治疗1疗程,判定疗效。[结果]临床疗效:治疗组显效21例,有效16例,无效3例,总有效率92.50%。对照组显效12例,有效17例,无效11例,总有效率72.50%。心电图疗效:治疗组显效22例,有效17例,无效1例,总有效率97.50%。对照组显效18例,有效13例,无效9例,总有效率77.50%。治疗组疗效优于对照组(P<0.05)。[结论]瓜蒌薤白半夏汤联合西药治疗痰浊闭阻型冠心病心绞痛疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Guluo Baibanxia Decoction combined with western medicine in treating phlegm-clotting coronary heart disease angina pectoris. [Method] Using random parallel control method, 80 outpatients and inpatients were randomly divided into two groups according to the coin tossing method. Control of diabetes, hypertension and hyperlipidemia, health education, avoid angina induced factors, anticoagulant, anti-platelet aggregation therapy. Control group, 40 cases of isosorbide dinitrate, 10mg / time, 2 ~ 3 times / d. The treatment group, 40 cases of melon 蒌 薤 white Pinellia soup (melon 蒌, Pueraria each 25g, white peony root 20g, Salvia, 薤 white each 15g, Pinellia, cassia twig, ginseng, turmeric, d, decoction 150mL, morning and evening oral, 75mL / time; western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, angina pectoris episodes, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] Clinical curative effect: In the treatment group, 21 cases were markedly effective, 16 cases were effective, 3 cases were ineffective, and the total effective rate was 92.50%. The control group markedly effective in 12 cases, effective in 17 cases, ineffective in 11 cases, the total effective rate was 72.50%. ECG effect: The treatment group was effective in 22 cases, effective in 17 cases, 1 case of ineffective, the total effective rate was 97.50%. In the control group, 18 cases were markedly effective, 13 cases were effective, 9 cases were ineffective, and the total effective rate was 77.50%. The treatment group was better than the control group (P <0.05). [Conclusion] The results showed that the curative effect of Guluo Baibanxia Decoction combined with western medicine on phlegm-dampness obstruction type angina pectoris was satisfactory and no serious side effects were observed, which deserved promotion.