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目的 探讨结直肠多原发癌的诊断与治疗。方法 通过4例病例并结合文献报道,讨论结直肠多原发癌的发病率、高危因素、诊断及治疗。结果 同时性结直肠多原发癌约占大肠癌2 %～6 % ,异时性结直肠多原发癌的发病率为0 . 6 %～9% ;其高危因素包括手术、放疗、遗传性非息肉病性结直肠癌和大肠多发腺瘤等;同时性结直肠多原发癌应避免漏诊,异时性结直肠多原发癌应避免误诊;常见手术方式有根治术、扩大根治术和全结肠切除术。结论 对该病应重视高危人群的监测,根治术加术后结肠镜长期随访是处理的适当选择。
Objective To investigate the diagnosis and treatment of multiple primary colorectal cancer. Methods Four cases combined with literature reports to discuss the incidence of multiple primary colorectal cancer, risk factors, diagnosis and treatment. Results Concurrent colorectal polycarcinoma accounts for about 2% to 6% of colorectal cancer, heterochromatic colorectal multiple primary cancer incidence of 0.6% to 9%; its risk factors include surgery, radiotherapy, hereditary Nonpolyposis colorectal cancer and multiple adenoma of the large intestine; simultaneous multi-primary colorectal cancer should be avoided misdiagnosis, heterogenous multiple primary cancer should be avoided misdiagnosis; common surgical methods are radical surgery, extended radical mastectomy and Total colon resection. Conclusion The monitoring of high risk population should be emphasized in this disease. Long-term follow-up of radical operation and colonoscopy is an appropriate treatment.