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西德海德堡大学医学院Ganten教授于1988年5月16日在阜外医院的报告中概述了血压调节机制研究的最新进展,着重阐述了神经肽这类既是循环激素又是神经递质的生理活性肽在心血管活动调节中的重要作用。在列举了脑啡肽、血管活性肠肽(VIP)、加压素、P物质、心钠素、血管紧张素、神经肽Y(neuropepride Y,NPY)、降钙素基因相关肽(calcitonin gene related peptide,CGRP)等调节肽的激素—递质双重功能后,特别强调了NPY和CGRP:前者的缩血管作用强于去甲肾上腺素而仅次于血管紧张
Professor Ganten of the University of Heidelberg Medical School in West Germany outlined the recent advances in the study of the mechanism of blood pressure regulation at the Fu Wai Hospital on May 16, 1988. The study focused on the physiological activities of neuropeptides, which are both circulating and neurotransmitters Peptides play an important role in the regulation of cardiovascular activity. Enkephalin, vasoactive intestinal peptide (VIP), vasopressin, substance P, atrial natriuretic peptide, angiotensin, neuropepride Y (NPY), calcitonin gene related peptide, CGRP) and other regulation of peptide hormone-transmitter dual function, with particular emphasis on NPY and CGRP: the former vasoconstrictor stronger than norepinephrine and second only to vascular tension