研究了一种微溶剂辅助高速球磨条件下的氧化Heck反应,用于高效制备2-乙烯基呋喃/噻吩化合物.这种钯催化氧化Heck偶联反应对丙烯酸酯和苯乙烯底物均具有较好的适用性,反应仅需45 min即可获得中等至较高收率的目标产物. A kind of Heck reaction catalyzed by micro-solvent assisted high-speed ball milling was studied for the efficient preparation of 2-vinylfuran / thiophene compound. This palladium-catalyzed oxidation Heck coupling reaction has good acrylate and styrene substrates Of the applicability of the reaction in just 45 minutes to obtain a medium to high yield of the target product.