应用放射免疫法测定血清激素值和透射电镜观察相应内分泌腺细胞超微结构变化,研究人参皂甙对冷束缚应激大鼠内分泌腺结构和功能的影响。实验组经腹腔注射入参皂甙,每天100mm/kg体重,连续5天,第6天冷束缚应激3小时后处死。实验结果表明,人参皂甙对冷束缚应激大鼠,具有抑制垂体-肾上腺轴的功能活动,促进生长激素大量分泌,增强机体的非特异抵抗力。 Radioimmunoassay was used to determine serum hormones and transmission electron microscopy to observe the changes in the ultrastructure of endocrine gland cells. The effects of ginsenosides on the structure and function of endocrine glands in cold-restraint rats were studied. The experimental group was intraperitoneally injected with ginsenosides, 100 mm/kg body weight per day, for 5 consecutive days, and sacrificed after 6 hours of cold restraint stress on the 6th day. The experimental results show that ginsenoside can inhibit the function of the pituitary-adrenal axis in cold-stressed rats, promote the secretion of a large number of growth hormone, and enhance the body’s non-specific resistance.