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目的对2007~2014年济南市急性脑炎脑膜炎疾病负担和经济负担进行调查研究,以期为济南市急性脑炎脑膜炎防控政策提供依据。方法使用济南市AMES专报系统2007~2014年的监测数据分析AMES的流行病学特征,并采用问卷调查方法,随访2013年报告的AMES患者,收集一般信息、病情转归、医疗和非医疗费用等估算AMES导致的经济负担。结果济南市2007~2014年AMES病例平均年报告发病率为8.49/10万,病死率4.96‰。全市AMES病例引起的失能损失为36 659.51个失能调整生命年(DALYs),人均8.27个DALYs。14岁以下人群占77.86%。AMES导致的人均经济负担为8.86万元,其中人均直接经济负担1.95万元,间接经济负担6.91万元。结论济南市急性脑炎脑膜炎病例所致流行病学负担和经济负担较重,应采取措施减轻发病和经济负担。
Objective To investigate the burden and economic burden of acute encephalitis meningitis in Jinan City from 2007 to 2014 so as to provide the basis for prevention and control of acute encephalitis meningitis in Jinan City. Methods The epidemiological characteristics of AMES were analyzed using monitoring data from 2007 to 2014 in AMES reporting system in Jinan. The questionnaires were used to follow up the AMES patients reported in 2013. General information, medical condition and non-medical expenses were collected Estimate the financial burden of AMES. Results The average annual incidence of AMES cases in Jinan from 2007 to 2014 was 8.49 per 100 000 and the case fatality rate was 4.96 per thousand. In the city, 36 659.51 disability-adjusted life years (DALYs) and 8.27 DALYs per capita were caused. People under the age of 14 accounted for 77.86%. The per capita economic burden caused by AMES was 88,600 yuan, of which the per capita direct economic burden was 19,500 yuan and the indirect economic burden was 69,100 yuan. Conclusion The epidemiological burdens and economic burden caused by acute encephalitis meningitis cases in Jinan are serious. Measures should be taken to reduce the incidence and financial burden.