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目的探讨提高分化型甲状腺癌(DTC)复发灶或转移灶检出率的最优化核素显像方法。方法对89例DTC患者的临床资料进行回顾性分析。核素显像方法包括血清甲状腺球蛋白(Tg)检查结合放射性碘(~(131)I)治疗剂量全身显像、~(99m)Tc-MIBI肿瘤显像和~(18)F-FDG带符合线路的SPECT/CT全身显像,对三种核素显像的结果进行对比分析。结果~(131)I治疗剂量全身显像、~(99m)Tc-MIBI肿瘤显像和~(18)F-FDG带符合线路的SPECT/CT全身显像的灵敏度分别为83.05%、79.66%和16.95%。结论~(99m)Tc-MIBI肿瘤显像和~(18)F-FDG带符合线路的SPECT/CT全身显像作为补充检查手段,可弥补血清Tg检查结合~(131)I全身显像的局限性,对DTC患者复发灶或转移灶的检出、疗效评估及进一步治疗方案的制定具有重要意义。
Objective To explore the optimal radionuclide imaging method for improving the detection rate of recurrent or metastatic lesions in differentiated thyroid cancer (DTC). Methods The clinical data of 89 patients with DTC were retrospectively analyzed. Radionuclide imaging methods included serum thyroglobulin (Tg) examination combined with radioiodine (~ (131) I) treatment at full body scintigraphy, 99m Tc-MIBI tumor imaging and 18F-FDG band coincidence Line SPECT / CT whole body imaging, the results of three radionuclide imaging were analyzed. Results The sensitivity of ~ (131) I whole body imaging, ~ (99m) Tc-MIBI tumor imaging and ~ (18) F-FDG coincidence imaging SPECT / CT whole body imaging were 83.05%, 79.66% 16.95%. Conclusion 99m Tc-MIBI tumor imaging and 18 F-FDG SPECT / CT whole body imaging with line coincidence can supplement the limitations of serum Tg combined with 131I whole body imaging Sex, DTC patients with recurrence or metastasis detection, efficacy evaluation and further treatment program is of great significance.