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目的研究肿瘤患者的血浆凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原(FIB),凝血酶时间(TT)四项指标测定在肿瘤治疗中的价值。方法采用德国BE康派XO全自动血凝分析仪检测120例肿瘤患者(其中肿瘤伴肝侵袭患者55例及肿瘤无肝侵袭患者65例)及80例正常对照组(正常体检且心、肝.肾功能的正常人)血凝四项指标。结果肿瘤伴肝侵袭患者的血凝检测指标与正常对照组相比有显著性差异(P<0.05),肿瘤无肝侵袭患者的血凝检测指标与正常对照组相比无显著性差异(P>0.05)。结论通过血凝检测的四项指标可以反映肿瘤患者的肝细胞受损程度等肝功能状况,为临床治疗提供有效数据,从而提高肿瘤患者的生命质量。
Objective To study the value of four indexes of tumor, including prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and thrombin time (TT) Methods 120 cases of cancer patients (including 55 cases with liver invasion and 65 cases without tumor invasion) and 80 normal control group (normal physical examination, heart and liver) were detected by German BE Kangpai XO automatic hemagglutination analyzer. Normal renal function) four indicators of blood clotting. Results The indexes of hemagglutination test in patients with liver invasion were significantly different from those in normal controls (P <0.05). There was no significant difference in the indexes of hemagglutination between patients with and without liver invasion (P> 0.05). Conclusion The four indexes which can be detected by hemagglutination can reflect the liver function of patients with hepatocellular carcinoma and provide effective data for clinical treatment so as to improve the quality of life of cancer patients.