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本文以抗－ＨＣＶ和ＨＣＶ－ＲＮＡ作为观察指标，对广州地区４２８例各类型慢性乙型肝炎患者的丙型肝炎病毒（ＨＣＶ）重叠感染状况进行血清流行病学调查。结果显示慢性乙型肝炎患者中ＨＣＶ重叠感染率为１０．１％，明显高于对照组的１．４％（Ｐ＝０．０００８）；慢重肝与肝硬化的重叠感染率高于慢迁肝与慢活肝（Ｐ＜０．０００１）；有输血史的患者ＨＣＶ重叠感染率高于无输血史者（Ｐ＜０．０００１）。
In this paper, anti-HCV and HCV-RNA as indicators of observation, Guangzhou 428 cases of various types of chronic hepatitis B patients with hepatitis C virus (HCV) over-infection status of serological epidemiological survey. The results showed that the prevalence of HCV infection was 10.1% in patients with chronic hepatitis B, which was significantly higher than that in controls (1.4%, P = 0.0008). The rates of overlap infection between chronic severe hepatitis and cirrhosis were higher than those of chronic patients Hepatic and slow-acting liver (P <0.0001). The prevalence of HCV infection in patients with a history of transfusion was higher than those without transfusion history (P <0.0001).