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目的:探讨双黄连口服液与雷尼替丁治疗口腔溃疡的临床效果。方法:按照随机数字表法将120例患者均分为实验组和对照组,对照组患者给予雷尼替丁联合维生素治疗,实验组患者在对照组基础上加用双黄连口服液,比较两组治疗效果。结果:实验组患者治疗后显效率和总有效率均明显高于对照组(P<0.05);实验组患者治疗后溃疡愈合和疼痛缓解时间均明显低于对照组(P<0.05);两组患者治疗后WBC、淋巴细胞水平均明显降低,与同组治疗前比较,差异具有显著性;实验组患者治疗后WBC、淋巴细胞水平明显低于对照组,差异具有显著性(P<0.05);实验组患者治疗后SIg A水平明显高于对照组,Ig G水平明显低于对照组,差异具有显著性;实验组患者口腔溃疡复发率为6.67%,对照组患者口腔溃疡复发率为16.67%(P<0.05)。结论:在雷尼替丁基础上应用双黄连口服液能够在短时间内改善患者疼痛症状,促进溃疡愈合,提高免疫功能,临床疗效显著。
Objective: To investigate the clinical effect of Shuanghuanglian oral solution and ranitidine in the treatment of oral ulcer. Methods: According to the random number table method, 120 patients were divided into experimental group and control group. The control group was given ranitidine combined with vitamin therapy. The experimental group was given Shuanghuanglian oral liquid on the basis of the control group. treatment effect. Results: The effective rate and total effective rate of the experimental group were significantly higher than those of the control group (P <0.05). The ulcer healing and pain relief time of the experimental group were significantly lower than that of the control group (P <0.05) The levels of WBC and lymphocyte in patients after treatment were significantly lower than those in the same group before treatment, and the levels of WBC and lymphocytes in the experimental group were significantly lower than those in the control group (P <0.05). The level of SIg A in the experimental group was significantly higher than that in the control group, while the level of Ig G in the experimental group was significantly lower than that in the control group. The rate of oral ulcer recurrence was 6.67% in the experimental group and 16.67% in the control group P <0.05). Conclusion: The application of ranitidine on the basis of Shuanghuanglian oral solution can be in a short period of time to improve the patient’s pain symptoms, promote ulcer healing, improve immune function, clinical efficacy significantly.