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目的 研究ＮＩＤＤＭ 患者骨密度的变化规律和临床特点。方法 使用双能Ｘ线吸收仪（ＤＥＸＡ）测定４８例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者腰２～４椎体正侧位和髋关节部位的骨密度，并与同性别３０～３５岁组对比，研究其骨密度的变化规律和临床特点。结果 ４８例中有２５例合并有骨质疏松，女性患者的骨密度下降程度明显高于男性患者；两组患者的髋关节部位骨密度下降程度均明显高于腰椎部位。结论 骨密度值与糖尿病病程、绝经后时间和年龄呈负相关。
Objective To study the changes and clinical features of bone mineral density (BMD) in patients with NIDDM. Methods Bone mineral density (BMD) was measured in 48 patients with non-insulin dependent diabetes (NIDDM) at the posterior aspect and in the hip joint using dual energy X-ray absorptiometry (DEXA), and compared with those of 30-35 years old , To study the changes of bone mineral density and clinical features. Results Of the 48 cases, 25 cases had osteoporosis. The bone mineral density in female patients was significantly lower than that in male patients. The bone mineral density of hip joint in both groups was significantly lower than that in lumbar region. Conclusion The BMD is negatively correlated with the course of diabetes, postmenopausal time and age.