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目的比较心理干预加抗抑郁、外用镇痛药物联合治疗方法与心理干预加非甾类药治疗纤维肌痛综症的临床疗效及不良反应。方法分别测定记录2组治疗前,治疗1、3个月末时视觉模拟标尺疼痛评分(VAS),纤维肌痛影响问卷调查评分(FIQ)变化。结果治疗组与对照组于治疗后1、3个月末时比较,VAS疼痛程度评分较基线明显下降(P<0.05、P<0.01);FIQ评分较基线下降,(P<0.05);且不良事件的发生与对照组比较有统计学差异。结论心理干预加阿米替林、扶他林乳膏的联合治疗,具有良好的协同作用,尤在治疗3个月时疗效明显,治疗组的总体效果明显优于对照组。
Objective To compare the clinical efficacy and adverse reactions of psychological intervention with antidepressant, topical analgesic combination therapy and psychological intervention with fibromyalgia syndrome. Methods The changes of visual analog scale pain score (VAS) and fibromyalgia on questionnaire score (FIQ) before and after the treatment of 1, 3 months were recorded and recorded in the two groups. Results The score of VAS pain decreased significantly (P <0.05, P <0.01), the FIQ score decreased from baseline (P <0.05), and the adverse events The occurrence of a statistically significant difference compared with the control group. Conclusion The combination of psychological intervention with amitriptyline and foxintarin cream has a good synergistic effect, especially in 3 months of treatment. The overall effect of the treatment group is obviously better than that of the control group.