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本文报道了56铡冠心病患者血浆β血栓球蛋白(βTG),血小板4因子(PF_4)、因子Ⅷ凝血活性(Ⅷ∶C)及相关抗原(ⅧR∶Ag)的变化。结果表明冠心病患者βTG血浆水平显著高于对照组,PF_4与对照组无显著差异,故βTG/PF_4比率显著增高,心肌梗塞心绞痛组尤为显著。冠心病患者ⅧR∶Ag浓度显著增高,而Ⅷ∶C与对照组无差异,ⅧR∶Ag/Ⅷ∶C之比率显著高于对照组,因此,同时测定βTG、PF_4或ⅧR∶Ag、Ⅷ∶C,并观察其比率的变化,可望对冠心病早期诊断及监护有一定的价值。
This article reports the changes of plasma β-thromboglobulin (βTG), platelet factor 4 (PF_4), factor Ⅷ coagulation activity (Ⅷ:C) and related antigen (ⅧR: Ag) in 56 patients with coronary heart disease. The results showed that patients with coronary heart disease βTG plasma levels were significantly higher than the control group, PF 4 and the control group no significant difference, so βTG / PF 4 ratio was significantly higher myocardial infarction group was particularly significant. Ⅷ: C was not significantly different from the control group, and the ratio of Ⅷ: Ag / Ⅷ: C was significantly higher than that of the control group. Therefore, βTG, PF_4 or ⅧR: Ag and Ⅷ: C , And observe the changes in its ratio, is expected to early diagnosis and monitoring of coronary heart disease have some value.