论文部分内容阅读
报道２０例次活动期类风湿关节炎病人的９９ｍＴｃ－人免疫球蛋白（ＨＩＧ）关节显像结果，其中 １６例与９９ｍＴｃ－ＭＤＰ显像进行了对照。结果表明，所有病人９９ｍＴｃ－ＨＩＧ显像均为异常，表现为 关节周围软组织即关节囊的放射性增高。它与临床的符合率明显高于９９ｍＴｃ－ＭＤＰ显像；每个病 人临床总分与其显像总分之间呈显著性相关（Ｐ＜０．０１，ｒ＝０．９３）；临床累及且显像阳性的关节， 其摄取放射性的多少与关节疼痛（或压痛、肿胀）程度之间，也有显著相关性（Ｐ＜０．０１）。 ９９ｍＴｃ－ＨＩＧ关节炎症显像是一种简便、安全、无创而客观的关节炎症检查方法。它能够灵敏 地探测滑膜炎症，反映疾病活动程度，帮助早期诊断类风湿关节炎，并且优于９９ｍＴｃ－ＭＤＰ。
The results of 99mTc-human immunoglobulin (HIG) joint imaging in 20 patients with sub-active rheumatoid arthritis were reported, of which 16 were compared with 99mTc-MDP imaging. The results showed that 99mTc-HIG imaging was abnormal in all patients, showing increased radioactivity in the soft tissue surrounding the joint, ie, the joint capsule. It was significantly higher than the clinical compliance rate with 99mTc-MDP imaging; each patient’s clinical score and its imaging score was significantly correlated (P <0.01, r = 0.93); clinical and significant There was also a significant correlation between the uptake of radioactivity and the degree of joint pain (or tenderness, swelling) in positive joints (P <0.01). 99mTc-HIG joint inflammation imaging is a simple, safe, non-invasive and objective joint inflammation test. It can sensitively detect synovial inflammation, reflect the degree of disease activity, to help early diagnosis of rheumatoid arthritis, and better than 99mTc-MDP.