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目的回顾性分析了本院自１９７８～１９９５年收治的１２例Ⅰ～Ⅱ期喉恶性淋巴瘤的治疗情况。方法全部病例均予局部放射治疗和全身化疗，放疗剂量４５～７２Ｇｙ（中位５７Ｇｙ），联合化疗方案包括ＣＯＰ、ＣＯＦ、ＣＨＯＰ（１～６疗程）。结果一、三、五年生存率分别为８３．３％、５７．１％、４５．７％（寿命表法）。２例治疗后半年内死于胃肠道淋巴瘤，１例治疗后５年出现扁桃体淋巴瘤。结论放疗和化疗的联合治疗对Ⅰ～Ⅱ期喉恶性淋巴瘤的预后较好。
Objective To retrospectively analyze the treatment of 12 cases of stage Ⅰ ~ Ⅱ laryngeal malignant lymphoma treated in our hospital from 1978 to 1995. Methods All cases were given local radiotherapy and systemic chemotherapy. The dose of radiotherapy was 45 ~ 72Gy (median 57Gy). The combined chemotherapy regimens included COP, COF and CHOP (1 ~ 6 courses). Results One, three and five-year survival rates were 83.3%, 57.1% and 45.7% respectively (life table method). Two patients died of gastrointestinal lymphoma within six months after treatment, and one patient developed tonsillar lymphoma five years after treatment. Conclusion The combination of radiotherapy and chemotherapy has a good prognosis for stage Ⅰ ~ Ⅱ laryngeal malignant lymphoma.