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许多致病因素都可引起胸腺病理性退化,已在大量的动物实验及人类疾病中得到证实。本文仅就58例围产儿死亡病例胸腺改变的观察,综合退化病变类型与死因、孕周、体重、年龄的关系,加以分析和讨论。资料与方法收集陕西省妇幼保健院1980年5月～1985年10月期间70例围产儿尸检中有胸腺及其它脏器资料较全者58例,其中新生儿45例,死产3例,死胎10例。所有切片HE染色,除明确死因外,着重观察胸腺改变,根据胸腺小叶缩小、皮髓质区分、皮质淋巴细胞坏变、减少的程度分为正常及轻度、中度、重度退化。
Many pathogenic factors can cause pathological degeneration of thymus has been confirmed in a large number of animal experiments and human diseases. This article only 58 cases of perinatal death of thymic changes observed, the integrated degenerative lesions and the cause of death, gestational age, weight, age, to be analyzed and discussed. Materials and Methods 58 cases of thymus and other organs in 70 cases of perinatal autopsy were collected from May 1980 to October 1985 in Shaanxi Maternal and Child Health Hospital. Among them, 45 cases were newborn, 3 cases were stillbirth, and stillbirth 10 cases. All sections were stained with HE, except for the specific cause of death, thymus changes were observed and divided into normal and mild, moderate and severe degeneration according to the reduction of thymus lobules, corticomedullary differentiation and cortical lymphocytic degeneration.