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目的观察扶正固本汤联合化疗治疗中晚期非小细胞肺癌的临床疗效。方法将65例患者随机分为治疗组(34例)与对照组(31例),两组均采用NC方案化疗,21d为1个周期;治疗组同时加用扶正固本汤口服。观察近期疗效、卡氏评分变化及不良反应。结果治疗组与对照组近期总缓解率分别为52.94%、29.03%(P<0.05);卡氏评分改善率治疗组与对照组分别为52.94%、16.13%(P<0.05);两组不良反应及毒性发生率差异无显著性(P>0.05)。结论扶正固本汤联合化疗治疗中晚期非小细胞肺癌可以提高临床疗效,提高生活质量。
Objective To observe the clinical effect of Fuzheng Guben Decoction combined with chemotherapy on advanced non-small cell lung cancer. Methods Sixty-five patients were randomly divided into treatment group (34 cases) and control group (31 cases). Both groups were treated with NC regimen and 21 days for one cycle. The treatment group was treated with Fuzheng Guben decoction. Observation of short-term efficacy, Karnofsky score changes and adverse reactions. Results The total remission rates of the treatment group and the control group were 52.94% and 29.03%, respectively (P <0.05). The improvement rate of the Karnofsky group was 52.94% and 16.13% (P <0.05) And no significant difference in the incidence of toxicity (P> 0.05). Conclusion Fuzheng Guben decoction combined with chemotherapy for advanced non-small cell lung cancer can improve clinical efficacy and improve quality of life.