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据统计,在工业国家,65岁以上老人死于心血管疾病和肿瘤者约占总死亡率的75%。然而关于膳食结构与生活方式因素与老年人总死亡率、冠心病、心血管病和肿瘤死亡率间关系远未清楚。本文意就单一或协同地中海膳食、生理活动、饮酒、吸烟等生活方式因素与老年人总死亡率或各种特殊原因死亡率间关系进行了分析。对象与方法本文为HALE、SENECA和FINE等3项有关老年人膳食、生活方式相关试验汇总分析,共纳入11个欧洲国家的1507例男性和832例女性健康老人,年龄70～90岁不等。旨在观察基线膳食结构和诸生活方式因素与随访10年间老年人总死亡率、冠心病、心血管病和肿瘤死亡危险间相关关系。结果在随访期间,总死亡人数935例,其中心血管病死亡371例,肿瘤死亡233例,其它原因死亡145例,不明原因死亡者186例。分析显示,基线地中海膳食(高蛋
According to statistics, in industrialized countries, deaths from cardiovascular diseases and cancer in people over the age of 65 account for about 75% of the total mortality. However, the relationship between dietary patterns and lifestyle factors and overall mortality in older adults, coronary heart disease, cardiovascular disease, and cancer mortality is far from clear. This article aims to analyze the relationship between lifestyle factors such as dietary or physical activity in the Mediterranean, drinking or smoking alone or in combination with total mortality in the elderly or various special causes. Subjects and Methods This study is a meta-analysis of three related trials on diet and lifestyle of the elderly, including HALE, SENECA and FINE. A total of 1507 males and 832 healthy females aged from 70 to 90 years were enrolled in 11 European countries. The purpose of this study was to examine the relationship between baseline dietary patterns and lifestyle factors and overall risk of death, coronary heart disease, cardiovascular disease, and cancer death over a 10-year follow-up. Results During follow-up, the total number of deaths was 935, including 371 cardiovascular deaths, 233 cancer deaths, 145 deaths from other causes and 186 unexplained deaths. Analysis shows that the baseline Mediterranean diet (high eggs