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目的:探讨无创压力支持通气在加强监护室(ICU)内的辅助撤机作用。方法:以2008年11月-2011年3月入住ICU接受气管插管机械通气的32例患者为研究对象,通气模式以同步间歇指令通气(SIMV)和压力支持通气(PSV)为基础,必要时联合呼气末正压(PEEP);根据患者的血气分析值,合理调整吸入氧浓度分数(FiO_2)、呼吸频率(RR)、吸气相压力(IPAP)、呼气相压力(EPAP)值,比较有创通气与无创通气状态下RR、心率(HR)、动脉血氧分压(PaO_2)、动脉血二氧化碳分压(PaCO_2)、pH、动脉血氧饱和度(SaO_2)值。结果:有创通气与无创通气各项监测指标均无明显变化(P>0.05),经无创通气过渡数日后均可离开ICU。结论:无创正压机械通气作为一种有效的撤机治疗方法,建议临床推广应用。
Objective: To explore the role of non-invasive pressure support ventilation in strengthening intensive care unit (ICU) within the role of weaning. METHODS: Thirty-two patients admitted to the ICU undergoing endotracheal intubation for mechanical ventilation from November 2008 to March 2011 were enrolled. Ventilation patterns were based on SIMV and PSV, (PEEP). According to the patient’s blood gas analysis value, the values of FiO2, RR, IPAP and EPAP were adjusted reasonably, The RR, heart rate (HR), arterial oxygen pressure (PaO_2), arterial carbon dioxide (PaCO_2), pH and arterial oxygen saturation (SaO_2) were compared between invasive ventilation and non-invasive ventilation. Results: There were no significant changes in the monitoring indicators of invasive ventilation and noninvasive ventilation (P> 0.05). After a few days of non-invasive ventilation, they could leave the ICU. Conclusion: Non-invasive positive pressure mechanical ventilation as an effective weaning treatment, it is recommended clinical application.