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目的：本文旨在探讨血清降钙素原和C反应蛋白对儿童1型糖尿病合并感染患者的诊断价值。方法选取2012年6月~2014年6月我院收住院1型糖尿病患儿167例,随机分为A、B、C三组。A组经细菌培养诊断合并细菌感染68例,B组经病毒抗体IgM检测诊断病毒感染者51例,C组1型糖尿病未合并感染48例。结果观察A组血清PCT和CRP水平明显高于观察B组及C组,差异有统计学意义(﹤0.05)。结论儿童1型糖尿病合并细菌感染时,血清PCT及CRP水平明显增高,对早期给予积极抗生素治疗控制感染,有重要指导意义。“,”Objective This paper is to investigate the changes of serum procalcitonin and C reactive protein in patients with diagnosis of infections in children with type 1 diabetes mel itus.Methods In our hospital in June 2012 to June 2014 hospitalized children with type 1 diabetes in 167 cases,were randomly divided into a,B,C three groups:group A,the bacterial culture for diagnosis of 68 cases complicated with bacterial infection,group B virus antibody IgM antibody in the diagnosis of viral infection in 51 cases,group C type 1 diabetes not associated with infection in 48 cases.Results In the observation group a serum PCT and CRP levels were significantly higher than those observed in group B and group C,the dif erence is statistical y significant ( ﹤0.05).Conclusion Children with type 1 diabetes mel itus complicated with bacterial infection,serum PCT and CRP levels were significantly increased,the early give antibiotic active treatment to control infection,and has important guiding significance.