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目的研究呼吸系统感染患者在急性肺炎衣原体感染的发病情况以及临床特征表现。方法选取220例住院患者均为呼吸系统感染,随机分为肺炎衣原体急性感染患者组50例和非肺炎衣原体急性感染患者组170例。采集标本为咽拭子以及痰标本,肺炎衣原体DNA的表达检测采用聚合酶链反应(PCR)进行检测,肺炎衣原体的IgG和IgM抗体表达情况采取静脉血进行检测。结果本研究呼吸系统感染患者的肺炎衣原体IgG抗体的阳性率为70%(154/220),联合应用两种方法的阳性表达率为23%(50/220)。肺炎衣原体患者的急性感染常以肺炎、支气管哮喘患者的急性发作、急性支气管炎患者的表现及慢性阻塞性肺疾病患者的急性加重表现为常见,其临床表现无特征性症状。结论本研究成年人呼吸系统感染的患者在肺炎衣原体患者急性感染的发病发生率较高,分析肺炎衣原体可能是呼吸系统感染的重要致病原。
Objective To study the incidence and clinical characteristics of acute respiratory syncytial infection in patients with respiratory infection. Methods A total of 220 hospitalized patients were selected as respiratory system and randomly divided into 50 cases of acute infection with Chlamydia pneumoniae and 170 cases of acute infection with non-Chlamydia pneumoniae. The collected samples were throat swabs and sputum samples. The expression of Chlamydia pneumoniae DNA was detected by polymerase chain reaction (PCR), and the expression of IgG and IgM antibodies against Chlamydia pneumoniae was detected by venous blood. Results The positive rate of Chlamydia pneumoniae IgG antibody in patients with respiratory infection was 70% (154/220) in this study, and 23% (50/220) in combination with the two methods. Acute infections of Chlamydia pneumoniae patients are often characterized by pneumonia, acute attacks of bronchial asthma, patients with acute bronchitis, and acute exacerbations of patients with chronic obstructive pulmonary disease, with no specific clinical manifestations. Conclusions The incidence of acute infection in patients with respiratory Chlamydia pneumoniae is high in patients with respiratory infections in this study. Analyzing Chlamydia pneumoniae may be an important causative agent of respiratory infection.