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目的探讨原发性高血压患者的运动训练与血心钠素(ANP)、一氧化氮(NO)及内皮素(ET)水平变化的关系。方法将62例原发性高血压病患者分为运动组(n=51)和对照组(n=11)。训练组进行为期7周,每周6次,每次1h的轻、中度运动训练。结果训练组患者运动后血压、ANP、NO及ET水平均显著下降,对照组无明显变化。结论运动训练可使原发性高血压患者的血压降低,ET、NO及ANP水平下降。
Objective To investigate the relationship between exercise training and the changes of blood atrial natriuretic peptide (ANP), nitric oxide (NO) and endothelin (ET) in patients with essential hypertension. Methods 62 patients with essential hypertension were divided into exercise group (n = 51) and control group (n = 11). Training group for a period of 7 weeks, 6 times a week, each 1h light and moderate exercise training. Results After exercise, the blood pressure, ANP, NO and ET levels in the training group decreased significantly, but there was no significant change in the control group. Conclusion Exercise training can reduce the blood pressure, ET, NO and ANP levels in patients with essential hypertension.