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探讨尿毒症患者血液流变学变化规律，为临床诊治尿毒症提供帮助，采用ＬＩＡＮＧ１００血液流变学仪测定２２例肾功能衰竭血液透析患者血液流变学指标。结果表明：尿毒症患者血液粘度较正常降低，其降低程度与红细胞压积呈正相关（Ｐ＜０．０１），与血肌酐水平呈负相关（Ｐ＜０．０１）。患者红细胞电泳时间明显延长（Ｐ＜０．００１），血沉方程Ｋ值与正常相比明显偏高（Ｐ＜０．００１）．表明红细胞聚集呈加快状态，分析可能与红细胞表面负电荷减少有关。红细胞高切粘度降低，提示红细胞变形性异于正常。血液流变学指标在一定程度上为临床诊断、治疗以及监测病情变化提供帮助。
To investigate the changes of hemorheology in patients with uremia and to provide assistance in the clinical diagnosis and treatment of uremia. The hemorrheological parameters of 22 patients with renal failure and hemodialysis were determined by LIANG100 hemorheology analyzer. The results showed that the blood viscosity of patients with uremia was lower than normal, the degree of decrease was positively correlated with hematocrit (P <0.01), and negatively correlated with serum creatinine (P <0.01). Patients with erythrocyte electrophoresis time was significantly longer (P <0.001), ESR K value was significantly higher than normal (P <0.001). Indicating that erythrocyte aggregation was accelerated state, the analysis may be related to the reduction of red blood cell surface charge. Reduce the viscosity of high-cut red blood cells, suggesting that abnormal red blood cell deformability. Hemorheology indicators to some extent for clinical diagnosis, treatment and monitoring of changes in the condition to help.