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目的:为有效对呼吸系统感染患者早期病症进行辨别诊断,探究采用血清降钙素原对患者进行检验的临床意义。方法:选取该院2014年3月至2015年6月期间呼吸内科收治的90例病患,分为PCT组与CRP组,按入院时间进行分配,每组45例。PCT组抽取病患静脉血对血清降钙素原进行检测,CRP组对C反应蛋白进行检测,对各组阳性标准下特异性、阳性预测值、敏感性、阴性预测值以及两种检查方式的准确度进行比较。结果:在阳性标准下PCT组灵敏度、阴性预测值、特异性、阳性预测值均高于CRP组(P<0.05);两种方式诊断准确度比较,PCT组检测准确度为88.9%,CRP组仅为73.3%,PCT组较CRP组检测准确度高(P<0.05)。结论:临床运用PCT对呼吸系统疾病患者进行检查准确度好、灵敏度高、特异性强,可有效判别患者是否为细菌感染所引发的疾病,临床可推广应用。
Objective: In order to effectively differentiate the early symptoms of patients with respiratory infections and to explore the clinical significance of using the serum procalcitonin to test the patients. Methods: Ninety patients admitted to Department of Respiratory Medicine from March 2014 to June 2015 in our hospital were divided into two groups: PCT group and CRP group, which were assigned according to the time of admission, with 45 cases in each group. In the PCT group, venous blood samples were collected to detect serum procalcitonin, C-reactive protein was detected in CRP group. Specificity, positive predictive value, sensitivity, negative predictive value and two test methods Accuracy for comparison. Results: The sensitivity, negative predictive value, specificity and positive predictive value of PCT group were higher than those of CRP group (P <0.05). The diagnostic accuracy of the two methods was 88.9% in PCT group, while the CRP group Only 73.3%. The detection accuracy of PCT group was higher than that of CRP group (P <0.05). Conclusion: The clinical application of PCT in the examination of patients with respiratory diseases with good accuracy, high sensitivity and specificity, which can effectively determine whether the patient is caused by bacterial infection, the clinical application can be promoted.