目的　探讨重症糖尿病患者血浆中甲状腺激素含量变化及临床意义。方法　应用放射免疫分析法测定 12 5例重症糖尿病患者和 6 0例健康人的血浆甲状腺激素含量。结果　重症糖尿病患者血浆T3 、FT3 含量明显低于健康人 ;死亡组T3 、FT3 含量与存活组有显著性差异。结论　监测重症糖尿病患者的血浆甲状腺激素水平可作为反映病情严重程度和估计预后的一项参考指标 Objective To investigate the plasma thyroid hormone content in patients with severe diabetes and its clinical significance. Methods Radioimmunoassay was used to detect plasma thyroid hormone levels in 125 patients with severe diabetes and 60 healthy individuals. Results Serum T3 and FT3 levels in patients with severe diabetes were significantly lower than those in healthy controls. The levels of T3 and FT3 in the death group were significantly different from those in survivors. Conclusion Monitoring thyroid hormone levels in patients with severe diabetes can be used as a reference index to reflect the severity of the disease and prognosis