酸可溶性蛋白(简称ASP)是肝脏合成的一种类糖蛋白。我们测定了293例健康成人及191例肝胆疾病血清ASP含量,结果表明正常人ASP均值为114.3mg/dl,参考范围为68～160mg/dl。191例患者中,ASP含量低于68mg/dl者,在急性病毒性肝炎中占21.2%,慢迁肝中占46.4%,慢活肝中占81.3%,重症肝炎中占85.7%,肝硬化中占89.4%,且可低至10mg/dl。而在18例原发性和继发性肝癌中,有12例血清ASP Acid-soluble protein (ASP) is a type of glycoprotein synthesized by the liver. We measured serum ASP levels in 293 healthy adults and 191 patients with hepatobiliary disease. The results showed that the normal mean ASP was 114.3 mg / dl and the reference range was 68 to 160 mg / dl. Of the 191 patients, those with an ASP of less than 68 mg / dl had 21.2% of acute viral hepatitis, 46.4% of slow-moving liver, 81.3% of slow-living liver, 85.7% of severe hepatitis, Accounting for 89.4% and can be as low as 10 mg / dl. In 18 cases of primary and secondary liver cancer, 12 cases of serum ASP