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作者研究了恶性疟疾补体激活与临床合并症及弥散性血管内凝血(DIC)发展之间的关系。共观察21例恶性疟患者,包括在原虫血症期间的18例和在疟原虫血症后1～5天的4例(其中1例在疟原虫血症期间也作了观察)。在原虫血症期间的18例病人中有6例有DIC,5例有多系统的合并症,7例没有全身性合并症。每个患者每天静脉注射碘化钠12毫克/公斤后3小时,静脉注射~(125)I标记的Clq(比活性1.9～2.2毫居里/克)和~(131)I标记的白蛋白(比活性0.33居里/克),总剂量不超过20微居里。然后用Veall等方法测定血浆中
The authors studied the relationship between complement activation of falciparum malaria and clinical complications and the development of disseminated intravascular coagulation (DIC). A total of 21 patients were observed for falciparum malaria, including 18 during parasitemia and 4 from 1 to 5 days after Plasmodium (1 was also observed during Plasmodium. Six of the 18 patients with protozoalosis had DIC, five had multiple system comorbidities, and seven had no generalized comorbidities. Each patient received intravenous injections of ~ (125) I-labeled Clq (specific activity 1.9-2.2 millicuries / gram) and ~ (131) I-labeled albumin Specific activity of 0.33 Curie / g), the total dose of not more than 20 micro-Curie. Then measured by Veall and other methods in the plasma