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原发性高血压患者６８例，盐酸苯那普利１０～２０ｍｇ／ｄ，少数治疗１周后疗效未达理想标准者加用适量钙拮抗剂或β－受体阻滞剂，疗程４周，观察其对原发性高血压的治疗作用以及对血脂、血糖等与高血压有关的血液因子的影响。结果显示，治疗后血压显著下降（Ｐ＜０．０１），同时可改善原发性高血压患者的肝肾功能和胰岛素抗性，而对心率和血脂无不良影响。认为，与其它血管紧张素转换酶抑制剂类药物一样，盐酸苯那普利有其独到的优势，有着良好的应用前景。
68 patients with essential hypertension, benazepril hydrochloride 10 ~ 20mg / d, after a few weeks of treatment less than the desired standard of efficacy with an appropriate amount of calcium antagonist or β-blockers for 4 weeks, To observe its therapeutic effect on essential hypertension as well as blood fat, blood sugar and other blood-related factors. The results showed that after treatment, blood pressure decreased significantly (P <0.01), while improving liver and renal function and insulin resistance in patients with essential hypertension, but no adverse effects on heart rate and blood lipids. That, like other angiotensin-converting enzyme inhibitors, benazepril hydrochloride has its unique advantages, has a good prospect.