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目的观察复方磷酸萘酚喹片治疗非洲恶性疟的临床效果。方法以显微镜血检恶性疟原虫阳性患者为观察对象。复方磷酸萘酚喹片顿服成人总量含磷酸萘酚喹400 mg及青蒿素1 000 mg。服药后按时测量体温和血检疟原虫。随访28d,观察治疗效果。结果复方磷酸萘酚喹片治疗非洲恶性疟35例,平均退热时间为(36.7±16.3)h,原虫转阴时间为(58.1±15.3)h,治愈率为97.3%,服药后除少数(2例)出现恶心、胃部不适外,无其它不良反应。结论复方磷酸萘酚喹片治疗非洲恶性疟具有良好的效果。
Objective To observe the clinical effect of compound naphthofluorescein in the treatment of falciparum malaria in Africa. Methods Microscopic examination of Plasmodium falciparum positive patients was used as the observation object. Compound Naphthol Quine Pelton served adults with total phosphorus naphthoquine 400 mg and artemisinin 1 000 mg. Measured on time after taking the body temperature and blood tests Plasmodium. Follow-up 28d, observe the effect of treatment. Results The results showed that 35 cases of falciparum malaria were treated with compound naphthoflurane in Africa, the mean time to fever was (36.7 ± 16.3) h, the time of protozoa was (58.1 ± 15.3) h, the cure rate was 97.3% Cases) nausea, stomach discomfort, no other adverse reactions. Conclusion Compound naphthoquine phosphate tablets in the treatment of falciparum malaria in Africa have good results.