目的　检验Fas配体在食管癌细胞的表达 ,及其与食管癌浸润淋巴细胞、与食管癌浸润与转移的关系和对病人术后生存的影响。方法　采用免疫组化方法检测 30例原发食管癌标本中Fas配体的表达 ,用CD4 5标记肿瘤浸润淋巴细胞。结果　 76 6 %的标本有Fas配体的表达 ,且不同TNM分期的病人表达水平差异显著 ,Fas配体的表达与食管癌中肿瘤浸润淋巴细胞数呈负相关 ,但Fas配体的表达与病人术后生存无显著关系。结论　Fas配体的表达有利于食管癌逃避免疫攻击 ,有利于其浸润与转移 Objective To examine the expression of Fas ligand in esophageal cancer cells and its relationship with infiltrating lymphocytes of esophageal cancer and its relationship with the invasion and metastasis of esophageal cancer and their postoperative survival. Methods Immunohistochemistry was used to detect the expression of Fas ligand in 30 primary esophageal cancer specimens. Tumor infiltrating lymphocytes were labeled with CD4 5. Results Sixty-six percent of the specimens had Fas ligand expression, and the expression levels of Fas ligand were significantly different in patients with different TNM stages. The expression of Fas ligand was negatively correlated with the number of tumor infiltrating lymphocytes in esophageal cancer, There was no significant relationship between postoperative survival. Conclusion The expression of Fas ligand is good for esophageal cancer to evade immune attack and facilitate its invasion and metastasis