目的:探讨鼓膜穿刺法内耳磁共振（MR）钆造影技术成功率、安全性和可重复性。方法:回顾性分析2010年2月至2020年6月于福建医科大学附属第一医院及福建中医药大学附属人民医院行鼓膜穿刺法内耳MR钆造影患者的影像和临床资料。所有病例在MR钆造影后门诊复查鼓膜及外耳道情况，以迷路是否有钆对比剂显影判断钆造影的成功与否。比较无症状耳在钆造影前后的纯音听阈资料；分析有复查的无症状耳2次造影中前庭、耳蜗和半规管得分及总分的一致性。结果:共纳入1 126例患者，男506例，女620例，年龄（54±17）岁，其中45例复查1次，4例复查2次。双侧同时检查958例，单侧检查168例。临床诊断典型梅尼埃病166例（14.7%），突发性聋219例（19.5%），眩晕待查741例（65.8%）。共2 084耳行首次钆造影，其中63耳迷路内未见对比剂，钆造影成功率97.0%（2 021/2 084）；随诊存在1例鼓膜穿孔，余无并发症；无症状耳57耳造影前后各频率听阈差异均无统计学意义（均n P>0.05），21耳前后2次造影前庭及耳蜗评分一致性良好，组内相关系数（ICC）均>0.75。n 结论:鼓膜穿刺法内耳MR钆造影技术成功率高，较安全，钆造影结果重复性良好。“,”Objective:To investigate the success rate, safety and repeatability of gadolinium (Gd)-enhanced inner ear magnetic resonance (MR) by tympanic membrane puncture.Methods:The imaging and clinical data of 1 126 cases with Gd-enhanced inner ear MR by tympanic membrane puncture from February 2010 to June 2020 were retrospectively analyzed. All cases were reexamined in the outpatient clinic after MR gadolinium contrast to check the tympanic membrane and external auditory canal. The success rate was identified by whether there was gadolinium contrast in the labyrinth. Meanwhile, the pure tone hearing threshold data of asymptomatic ears before and after gadolinium contrast was collected and compared. The consistency in the scores of the asymptomatic ears in patients who underwent twice Gd-enhanced MR was analyzed, in which the scores of vestibular, cochlea, and semicircular canals were acquired respectively.Results:Among 1 126 patients [including 506 males and 620 females, aged (54±17) years old], 45 were reviewed once, while 4 patients were reviewed twice. There were 958 cases who were examined on both sides, and 168 cases were checked only on one side. There were 166 cases of Meniere′s disease (14.7%), 219 cases of sudden sensorineural hearing loss (19.5%) and 741 cases of being remained to be investigated (65.8%), respectively. A total of 2 084 ears underwent first gadolinium angiography, of which 63 ears had no contrast agent in the labyrinth, with a success rate of 97.0% (2 021/2 084). Only 1 case had tympanic membrane perforation while the rest had no complications. The hearing threshold before and after otography in 57 asymptomatic ears had no differences at any frequency (all n P>0.05). Moreover, the consistency in the scores of two radiography within the 21 asymptomatic ears in vestibular and cochlea was good [both intraclass correlation coefficient (ICC) values>0.75].n Conclusion:The success rate and safety of Gd-enhanced inner ear MR is high by tympanic membrane puncture, and the results can be repeated well.