应用流式细胞术对57例卵巢上皮性癌,进行了细胞DNA含量测定并探讨其临床意义。结果:晚期痛异倍体率(77.7%)高于早期者(9.5%),P<0.01,且细胞增殖活跃。多因素分析显示DNA含量是影响预后的最重要因素,P=0.007,二倍体肿瘤患者生存时间长。本文认为DNA含量反映了肿瘤自身的生物学特性,DNA倍体测量有助于了解病人预后。 57 cases of ovarian epithelial carcinoma were analyzed by flow cytometry and their clinical significance was determined. Results: The rates of aneuploidy in advanced stage pain (77.7%) were higher than those in early stage (9.5%), P <0.01, and cell proliferation was active. Multivariate analysis showed that DNA content was the most important factor affecting prognosis, P = 0.007, and patients with diploid tumors had longer survival time. In this paper, DNA content reflects the biological characteristics of the tumor itself, DNA ploidy measurement helps to understand the prognosis of patients.