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[目的]对脊柱骨巨细胞瘤患者的临床诊治进行回顾性分析,为其诊治提供参考。[方法]选取2005～2010年间来本院确诊为脊柱骨巨细胞瘤患者20例,其中骶骨和椎骨骨巨细胞瘤患者各10例,分析脊柱骨巨细胞瘤患者年龄、性别、患病节段等9项指标。[结果]骶骨骨巨细胞瘤患者男、女性各5例,平均年龄31岁;椎骨骨巨细胞瘤患者男性4,女性6例;平均年龄42岁;骶骨骨巨细胞瘤患者中有6例患者进行了术前栓塞术;椎骨骨巨细胞瘤主要以外科手术切除为主;两组均有2例复发,无死亡和肺转移病例。[结论]手术切除对于椎骨骨巨细胞瘤具有很好的作用;在术前栓塞后再做局部切除;术后放疗对于降低骶骨骨巨细胞瘤的复发率具有一定的意义;CT引导下针吸活组织检查对于骨巨细胞瘤的术前诊断具有很好的价值。
[Objective] To retrospectively analyze the clinical diagnosis and treatment of patients with giant cell tumor of bone of the spine and to provide reference for their diagnosis and treatment. [Methods] Twenty cases of giant cell tumor of the spine were diagnosed in our hospital from 2005 to 2010, including 10 cases of giant cell tumor of the sacrum and vertebra respectively. The age, sex and diseased segments of giant cell tumor of the spine were analyzed 9 indicators. [Results] There were 5 males and 5 females, each with a mean age of 31 years. The patients with giant cell tumor of the vertebra were 4 males and 6 females, with an average age of 42 years. Six patients with sacral giant cell tumor of the sacrum Preoperative embolization was performed. Vertebral giant cell tumor of the vertebra was mainly treated by surgical resection. There were two cases of recurrence in both groups, with no death or lung metastases. [Conclusion] Surgical resection has a good effect on giant cell tumor of vertebrae. Partial embolectomy is performed before embolization. Postoperative radiotherapy has certain significance for reducing the recurrence rate of sacral giant cell tumor. CT-guided needle aspiration Biopsy is of great value in the preoperative diagnosis of giant cell tumor of bone.